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bioRxiv · 10.1101/439323

Bioorthogonal Antigens Allow The Study Of Intracellular Processing And Presentation Of Post-Translationally Modified Antigens

Araman, C. M. C.·Pieper-Pournara, L.·Kampstra, A. S. B.·Marqvorsen, M. H. S.·Nascimento, C.·van der Wulp, W.·Groenewold, M. G. J. M.·Camps, M. G. M.·Ossendorp, F.·Toes, R.·van Kasteren, S. I.
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Abstract

Proteolysis is fundamental to many biological processes. In the immune system, it underpins the activation of the adaptive immune response: degradation of antigenic material into short peptides and presentation thereof on major histocompatibility complexes, leads to activation of T-cells. This initiates the adaptive immune response against many pathogens.

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Araman, C. M. C., Pieper-Pournara, L., Kampstra, A. S. B., Marqvorsen, M. H. S., Nascimento, C., van der Wulp, W., Groenewold, M. G. J. M., Camps, M. G. M., Ossendorp, F., Toes, R., van Kasteren, S. I.. 2018-10-11. Bioorthogonal Antigens Allow The Study Of Intracellular Processing And Presentation Of Post-Translationally Modified Antigens. https://doi.org/10.1101/439323

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