Bioorthogonal Antigens Allow The Study Of Intracellular Processing And Presentation Of Post-Translationally Modified Antigens
Proteolysis is fundamental to many biological processes. In the immune system, it underpins the activation of the adaptive immune response: degradation of antigenic material into short peptides and presentation thereof on major histocompatibility complexes, leads to activation of T-cells. This initiates the adaptive immune response against many pathogens.
immunology↗