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bioRxiv · 10.1101/2022.10.04.510918

Rapid inactivation of vaccinia, a surrogate virus for monkeypox and smallpox, using ultraviolet-C disinfection

Koutras, C.·Wade, R. L.
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Abstract

Human monkeypox is an emerging health threat that has the potential to cause serious sequelae. Ultraviolet-C (UV-C) disinfection is a physical process that triggers microbial inactivation through irreversible DNA damage. A high-output mobile UV-C unit was evaluated against vaccinia, a monkeypox surrogate, for antimicrobial efficacy. In under 7 minutes, a single UV-C cycle had a virucidal efficacy of [≥] 99.996 % in a 200 sq feet area. UV-C technology is a promising strategy for infection prevention and control in the post-COVID era.

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Koutras, C., Wade, R. L.. 2022-10-05. Rapid inactivation of vaccinia, a surrogate virus for monkeypox and smallpox, using ultraviolet-C disinfection. https://doi.org/10.1101/2022.10.04.510918

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