Heat inactivation of the Monkeypoxvirus

Batejat, C.; Grassin, Q.; Feher, M.; Hoinard, D.; Vanhomwegen, J.; Manuguerra, J.-C.; Leclercq, I.

doi:10.1101/2022.08.10.502482

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bioRxiv · 10.1101/2022.08.10.502482

Heat inactivation of the Monkeypoxvirus

Batejat, C.·Grassin, Q.·Feher, M.·Hoinard, D.·Vanhomwegen, J.·Manuguerra, J.-C.·Leclercq, I.

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Abstract

Different kinds of media spiked with Monkeypoxvirus (MPXV) were subjected to heat inactivation at different temperatures, for various periods of time. Our results showed that MPXV was inactivated in less than 5 min at 70 {degrees}C and in less than 15 min at 60 {degrees}C, with no difference between virus from West African and Central African clades. Such indications could help laboratory workers to manipulate the virus in optimal biosafety conditions and improve their protocols.

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Batejat, C., Grassin, Q., Feher, M., Hoinard, D., Vanhomwegen, J., Manuguerra, J.-C., Leclercq, I.. 2022-08-10. Heat inactivation of the Monkeypoxvirus. https://doi.org/10.1101/2022.08.10.502482

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