Phase transitions in tumor growth: II prostate cancer cell lines

José Llanos Pérez; Juvencio A Betancourt Mar; María P De Miguel; Elena Izquierdo Kulich; Mar Royuela García; Eduardo Tejera; José M Nieto Villar

doi:10.1101/011189

bioRxiv · 10.1101/011189

Phase transitions in tumor growth: II prostate cancer cell lines

José Llanos Pérez·Juvencio A Betancourt Mar·María P De Miguel·Elena Izquierdo Kulich·Mar Royuela García·Eduardo Tejera·José M Nieto Villar

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Abstract

We propose a mechanism for prostate cancer cell lines growth, e.g., LNCaP and PC3 based on a Gompertz dynamics. This growth exhibits a multifractal behavior and a \"second order\" phase transition. Finally, it was found that the cellular line PC3 exhibits a higher value the entropy production rate compared to LNCaP, which is indicative of the robustness of PC3, over to LNCaP and may be a quantitative index of metastatic potential tumors.\n\nHighlightsO_LICancer is an open, complex, dynamic and self-organizing system.\nC_LIO_LIProstate cancer cell lines growth follows a Gompertz dynamics\nC_LIO_LIProstate cancer cell lines exhibit a multifractal behavior\nC_LIO_LIThe entropy production rate may be considered as metastatic potential marker\nC_LI

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José Llanos Pérez, Juvencio A Betancourt Mar, María P De Miguel, Elena Izquierdo Kulich, Mar Royuela García, Eduardo Tejera, José M Nieto Villar. 2014-11-06. Phase transitions in tumor growth: II prostate cancer cell lines. https://doi.org/10.1101/011189

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