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Coppard, V.

Publications and source records attributed to Coppard, V..

2 recordsLinked to original sources

34-parameter full spectrum immunophenotyping panel of human regulatory and effector lymphocytes

This 34-marker sentinel, intracellular, full-spectrum flow cytometry panel profiles regulatory and effector T, B and NK lymphocytes in human cryopreserved peripheral blood mononuclear cells. The panel focuses on cell trafficking, activation, exhaustion and proliferation, and permits easy customisation in two positions to accommodate other targets of the users interest. By combining breadth and depth of phenotyping, this panel is designed to maximise the information obtained from limited cell material and therefore will be particularly useful in mechanistic studies of immunomodulatory drugs for autoimmune disease, cancer and transplantation, where multiple immune populations may be affected.

immunology↗

FlowAtlas.jl: an interactive tool bridging FlowJo with computational tools in Julia

As the dimensionality, throughput, and complexity of cytometry data increases, so does the demand for user-friendly, interactive analysis tools that leverage high-performance machine learning frameworks. Here we introduce FlowAtlas.jl: an interactive web application that bridges the user-friendly environment of FlowJo and computational tools in Julia developed by the scientific machine learning community. We demonstrate the capabilities of FlowAtlas using a novel human multi-tissue, multi-donor immune cell dataset, highlighting key immunological findings.

bioinformatics↗