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bioRxiv · 10.64898/2026.08.20.746062

Neural correlates of location-response compatibility in an immersive virtual-reality Attention Network Test: a multiverse electroencephalography analysis

Tekampe, D. L.·Santangelo, P. S.·Sulaj, A.·Tekampe, P.·Schwartze, M.·Hausfeld, L.
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Abstract

Immersive virtual reality (VR) can preserve the logic of laboratory attention tasks while altering the perceptual-action context in which attentional control is expressed. In this study, we examined the neural underpinnings of location-response compatibility in a VR adaptation of the Attention Network Test-Revised (ANT-VR), using a restricted preprocessing multiverse to account for uncertainty arising from defensible EEG analysis choices. Forty-four young adults contributed complete ANT-VR behavioural data. Target-locked EEG analyses were conducted across 192 preprocessing branches, with branch-level participant contributions varying after quality check and trial-count filtering. The contrast compared location-response incompatible with compatible trials and was balanced within participants across cue-target interval, cue condition, flanker congruency, and, for spatial-cue trials, conditions in which spatial cues were valid or invalid for subsequent targets. Across the multiverse, the N2pc-window posterior-lateralisation contrast could be defined in all branches and showed high directional stability: the median incompatible-minus-compatible effect was 0.30 uV [IQR: 0.22 to 0.41], with positive effects in 192/192 branches, nominal evidence in 79/192 branches, and Holm-corrected evidence in 42/192 branches. Comparison across ERP measures indicated that this pattern was more consistent for N2pc-window posterior lateralisation than for P1, posterior N1, frontocentral N2, P3, or response-referenced C3/C4 measures. Comparison across C3/C4 reference frames further constrained the interpretation: target-location-referenced C3/C4 showed the strongest effect, whereas response-referenced C3/C4 was weaker. Behavioural analyses showed no reliable compatibility differences. These findings suggest that location-response compatibility in immersive ANT-VR modulates target-locked lateralised neural activity associated with spatial selection and target-location coding, rather than producing broad sensory, conflict-related, P3-related, or specifically response-referenced modulation.

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Tekampe, D. L., Santangelo, P. S., Sulaj, A., Tekampe, P., Schwartze, M., Hausfeld, L.. 2026-08-25. Neural correlates of location-response compatibility in an immersive virtual-reality Attention Network Test: a multiverse electroencephalography analysis. https://doi.org/10.64898/2026.08.20.746062

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