The Q1K Integrated EEG and Eye-Tracking Experimental Test Battery for Open Autism Science

O'Reilly, C.; Desjardins, J.; Blanco-Gomez, G.; Huberty, S.; Loewen, A. H. P.; Ramnani, S.; Srishyla, D.; Knoth, I. S.; Martin, C.-O.; Batten, J. P.; van Noordt, S.; Hebert-Lalonde, N.; Samson, F.; Smith, T. J.; Forgeot d'Arc, B.; Ernst, C.; Carter, M. T.; Tardif, C. L.; Scorah, J.; Couture, M.; Abadie, P.; Joober, R.; Jacquemont, S.; Rouleau, G. A.; Lippe, S.; Elsabbagh, M.

doi:10.64898/2026.07.13.738272

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bioRxiv · 10.64898/2026.07.13.738272

The Q1K Integrated EEG and Eye-Tracking Experimental Test Battery for Open Autism Science

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Abstract

The Quebec 1000 Families (Q1K) platform has been designed to recruit, phenotype, and collect biospecimens from a large cohort of families with at least one member with autism spectrum disorder or a related neurodevelopmental condition. As part of the Q1K protocol, an experimental test battery was developed and validated using simultaneous high-density electroencephalography (EEG) and eye tracking (ET). We report on the general approach and design principles, multimodal EEG/ET integration, the tasks, and their validation, providing a blueprint for implement such a project. It also describes the cohort and its methods as a reference for future studies using this dataset. By releasing openly this experimental test battery, we aim to support task standardization and multi-project data pooling in autism and related neurodevelopmental disorders.

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O'Reilly, C., Desjardins, J., Blanco-Gomez, G., Huberty, S., Loewen, A. H. P., Ramnani, S., Srishyla, D., Knoth, I. S., Martin, C.-O., Batten, J. P., van Noordt, S., Hebert-Lalonde, N., Samson, F., Smith, T. J., Forgeot d'Arc, B., Ernst, C., Carter, M. T., Tardif, C. L., Scorah, J., Couture, M., Abadie, P., Joober, R., Jacquemont, S., Rouleau, G. A., Lippe, S., Elsabbagh, M.. 2026-07-20. The Q1K Integrated EEG and Eye-Tracking Experimental Test Battery for Open Autism Science. https://doi.org/10.64898/2026.07.13.738272

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