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bioRxiv · 10.1101/721118

A comparison of pedigree, genetic, and genomic estimates of relatedness for informing pairing decisions in two critically endangered birds.

Abstract

Conservation management strategies for many highly threatened species include conservation breeding to prevent extinction and enhance recovery. Pairing decisions for these conservation breeding programmes can be informed by pedigree data to minimise relatedness between individuals in an effort to avoid inbreeding, maximise diversity, and maintain evolutionary potential. However, conservation breeding programmes struggle to use this approach when pedigrees are shallow or incomplete. While genetic data (i.e., microsatellites) can be used to estimate relatedness to inform pairing decisions, emerging evidence indicates this approach lacks precision in genetically depauperate species, and more effective estimates will likely be obtained from genomic data (i.e., thousands of genome-wide single nucleotide polymorphisms, or SNPs). Here, we compare relatedness estimates using pedigree-, genetic-, and genomic-based approaches for making pairing decisions in two critically endangered birds endemic to New Zealand: kak[i]/black stilt (Himantopus novaezelandiae) and k[a]k[a]riki karaka/orange-fronted parakeet (Cyanoramphus malherbi). Our findings indicate genetic-based estimates of relatedness are indeed the least precise when assessing known parent-offspring and full sibling relationships. Furthermore, our results show that relatedness estimates and subsequent pairing recommendations using PMx are most similar between pedigree- and genomic-based approaches. These combined results indicate that in lieu of robust pedigrees, SNPs are an effective tool for informing pairing decisions, which has exciting implications for many poorly pedigreed conservation breeding programmes worldwide.

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BibTeXRIS

Galla, S. J., Moraga, R., Brown, L., Cleland, S., Hoeppner, M., Maloney, R. F., Richardson, A., Slater, L., Santure, A. W., Steeves, T. E.. 2019-07-31. A comparison of pedigree, genetic, and genomic estimates of relatedness for informing pairing decisions in two critically endangered birds.. https://doi.org/10.1101/721118

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