MicrobComp - graphical user interface enables an in-silico comparison of taxonomic differences between two amplicon datasets

Nussbaumer, T.

doi:10.1101/717231

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bioRxiv · 10.1101/717231

MicrobComp - graphical user interface enables an in-silico comparison of taxonomic differences between two amplicon datasets

Nussbaumer, T.

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Abstract

The experimental and computational analysis of microbes is in the focus of basic and applied research for several decades already and has massively extended our knowledge of role and impact of microbes during that time.\n\nAmplicon sequencing is still widely adapted and standard procedure to determine key species in a biological sample and despite a high number of different datasets being steadily generated and fed into current data archives, there is a shortcoming in data interpretation. Furthermore, more computational tools are still required to guide the researcher towards an in-depth understanding of an experiment in a more systematic way. Towards that aim, MicrobComp was created as a graphical user interface which allows to compare two separate species frequency tables that contain the relative or absolute abundance of microbial species in an experiment. Therefore, this tool can be of great help when studying different amplicon experiments where studies were originally performed in different experimental labs.

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Nussbaumer, T.. 2019-07-28. MicrobComp - graphical user interface enables an in-silico comparison of taxonomic differences between two amplicon datasets. https://doi.org/10.1101/717231

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