Quantifying cell line specific proliferation and migration rates in glioblastoma cells

Rosen, E.; Gerlee, P.; Nelander, S.

doi:10.1101/654053

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Quantifying cell line specific proliferation and migration rates in glioblastoma cells

Rosen, E.·Gerlee, P.·Nelander, S.

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Abstract

We have characterised the migration and proliferation rates of a large number of patient-derived glioblastoma cell lines using an individual-based model coupled to an Approximate Bayesian Computation algorithm. We found that the cell lines exhibited a negative correlation between the rate of migration and rate of division. This observation agrees with the Go or Grow hypothesis and highlights patient-specific differences in migration and proliferation.

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Rosen, E., Gerlee, P., Nelander, S.. 2019-05-29. Quantifying cell line specific proliferation and migration rates in glioblastoma cells. https://doi.org/10.1101/654053

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