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bioRxiv · 10.1101/652545

Low handgrip strength is closely associated with anemia among adults: A cross-sectional study using Korea National Health and Nutrition Examination Survey (KNHANES)

Gi, Y.-m.·Jung, B.·Kim, K.-W.·Cho, J.-H.·Ha, I.-H.
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Abstract

BackgroundAnemia occurs because of insufficient hemoglobin, which provides oxygen to the body. Because of its close relationship with various illnesses, it must always be investigated clinically. Previous studies have demonstrated an association between hemoglobin concentration and handgrip strength. Thus, we aimed to analyze the association between handgrip strength and anemia in Korean adults to determine whether the handgrip strength test can be used as a tool to identify anemia.\n\nMethodsThe research subjects data were extracted from the 6th and 7th Korean National Health and Nutrition Examination Survey, between January 2013 and December 2017. Overall, data of 16,637 adults (weighted n= 9,734,598) were analyzed. Differences in sociodemographic factors (sex, age, education, income, and employment), lifestyle factors (alcohol consumption, smoking, and physical activity), and illness and health factors (body mass index, vitamin intake, iron intake, comorbid illnesses, and handgrip strength) by existence of anemia were analyzed using a chi square test. Binary logistic regression was performed to identify factors of anemia. Subgroup analysis, stratified by sex and age, was performed.\n\nResultsAmong Korean adults aged [≥] 19 years, 745,296 (7.7%) had anemia. Higher odds ratio (OR) of anemia occurred in the weak handgrip strength group compared to the strong handgrip strength group (OR=1.92, 95% CI: 1.58-2.33). The subgroup analysis showed a higher OR for anemia in the weak handgrip strength group than in the strong handgrip strength group, regardless of sex or age. However, the results showed that this association was greater for males (OR=2.13, 95% CI: 1.35-3.34) and for those aged [≥]65 years (OR=1.92, 95% CI: 1.42-2.58).\n\nConclusionThis study showed a strong association between handgrip strength and anemia, which was particularly strong for males and those aged [≥]65 years. Therefore, it is anticipated that handgrip strength can be used in anemia screening tests as a useful tool.

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Gi, Y.-m., Jung, B., Kim, K.-W., Cho, J.-H., Ha, I.-H.. 2019-05-29. Low handgrip strength is closely associated with anemia among adults: A cross-sectional study using Korea National Health and Nutrition Examination Survey (KNHANES). https://doi.org/10.1101/652545

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