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bioRxiv · 10.1101/628131

Induced illusory body ownership in Borderline Personality Disorder

Neustadter, E. S.·Fineberg, S. K.·Leavitt, J.·Carr, M. M.·Corlett, P. R.
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Abstract

BackgroundOne aspect of selfhood that may have relevance for Borderline Personality Disorder (BPD) is variation in sense of body ownership. We employed the rubber hand illusion (RHI) to manipulate sense of body ownership in BPD. We extended previous research on illusory body ownership in BPD by testing: 1) two illusion conditions: asynchronous & synchronous stimulation, 2) relationship between Illusion experience and BPD symptoms, and 3) relationship between illusion experience and maladaptive personality traits.\n\nMethodsWe measured illusion strength (questionnaire responses), proprioceptive drift (perceived shift in physical hand position), BPD symptoms (DIB-R score), and maladaptive personality traits (PID-5) in 24 BPD and 21 control participants.\n\nResultsFor subjective illusion strength, we found a main effect of group (BPD > HC, F = 11.94 p = 0.001), and condition (synchronous > asynchronous, F(1,43) = 22.80, p < 0.001). There was a group x condition interaction for proprioceptive drift (F(1,43) = 6.48, p = 0.015) such that people with BPD maintained illusion susceptibility in the asynchronous condition. Borderline symptom severity correlated with illusion strength within the BPD group, and this effect was specific to affective symptoms (r = 0.48, p < 0.01). Across all participants, trait psychoticism correlated with illusion strength (r = 0.44, p < 0.01).\n\nConclusionPeople with BPD are more susceptible to illusory body ownership than controls. This is consistent with the clinical literature describing aberrant physical and emotional experience of self in BPD. A predictive-coding framework holds promise to develop testable mechanistic hypotheses for disrupted bodily self in BPD.\n\nHighlightsO_LIThe rubber hand illusion (RHI) allows measurement of self-disturbance.\nC_LIO_LIPeople with BPD had greater illusion susceptibility and this correlated with affective symptoms.\nC_LIO_LIInteroception stabilizes representations of body ownership, and is impaired in BPD.\nC_LIO_LIIllusion strength correlates with psychotic traits across levels of psychopathology.\nC_LIO_LIPredictive coding frameworks can probe mechanisms of impaired body ownership in psychopathology.\nC_LI

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Neustadter, E. S., Fineberg, S. K., Leavitt, J., Carr, M. M., Corlett, P. R.. 2019-05-05. Induced illusory body ownership in Borderline Personality Disorder. https://doi.org/10.1101/628131

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