Prevalence, awareness and control of hypertension in Malaysia 1980 - 2017: A Systematic Review and Meta-Analysis

Chow, Z. Y.; Soo, M. J.; Ching, S. M.; Tan, C. H.; Lee, K. W.; Devaraj, N. K.; Salim, H. S.; Ramachandran, V.; Hoo, F. K.; Cheong, A. T.; Chia, Y. C.

doi:10.1101/625004

bioRxiv · 10.1101/625004

Prevalence, awareness and control of hypertension in Malaysia 1980 - 2017: A Systematic Review and Meta-Analysis

Chow, Z. Y.·Soo, M. J.·Ching, S. M.·Tan, C. H.·Lee, K. W.·Devaraj, N. K.·Salim, H. S.·Ramachandran, V.·Hoo, F. K.·Cheong, A. T.·Chia, Y. C.

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Abstract

BackgroundHypertension is a common public health problem worldwide and is a well-known risk factor for increased risk of cardiovascular diseases, contributing to high morbidity and mortality. However, there is no systematic review and meta-analysis that has been done in a multi-ethnic population like Malaysia. This systematic review aims to determine the trend in prevalence, awareness and control of hypertension in Malaysia.\n\nMethodsSystematic searches were conducted in PubMed, Scopus, Ovid, Cumulative Index to Nursing and Allied Health Literature, Malaysian Medical Repository and Malaysia Citation Index published between 1980 and 2017. All original articles in English were included. Studies included were those on adults aged 18 years and above. Studies of prevalence in children and adolescents and pregnancy related hypertension were excluded. Two authors independently reviewed the studies, carried out data extraction and performed quality assessment. Heterogeneity between studies and publication bias was assessed and effect size was pooled by the random effect model.\n\nResultsFifty-six studies with a total of 241,796 subjects were included. The prevalence of hypertension throughout Malaysia varied (I2 = 99.3%). The overall pooled prevalence of hypertension over the past 4 decades was 28.2% in adults aged 18 years and older (95% CI: 26.1 - 33.3) and the prevalence in those 30 years and older was 40.0% (95% CI: 35.3-44.8).\n\nFor subgroup analysis, the prevalence of hypertension in male aged 18 and above was 31.4% (95% CI: 26.5 - 36.2) and 27.8% in female (95% CI: 20.7 - 34.9). The prevalence of hypertension among the ethnic groups aged 18 years and above were 37.3% in Malays (95% CI: 32.9 - 41.7); 36.4% in Chinese (95% CI 31.6 - 41.2) and 34.8% in Indians (95% CI: 31.2-38.4). The prevalence of hypertension was the lowest in the 1980s (16.2%, 95% CI: 13.4-19.0%), increases up to 36.8% in the 1990s (95% CI: 6.1-67.5), then came down to 28.7% (95% CI: 21.7-35.8) in the 2000s and 29.2% (95% CI: 24.0-34.4) in the 2010s. The prevalence of awareness was 38.7% (95% CI: 31.7 - 45.8) whereas the control of hypertension of those on treatment was 33.3% (95% CI: 28.4 - 38.2).\n\nConclusionThree in 10 adults aged 18 years old and above have hypertension, whereas four in 10 adults aged 30 years old and above have hypertension. Four out of 10 are aware of their hypertension status and only one-third of them who were under treatment achieved control of their hypertension. Concerted efforts by policymakers and healthcare professionals to improve the awareness and control of hypertension should be of high priority.

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Chow, Z. Y., Soo, M. J., Ching, S. M., Tan, C. H., Lee, K. W., Devaraj, N. K., Salim, H. S., Ramachandran, V., Hoo, F. K., Cheong, A. T., Chia, Y. C.. 2019-05-01. Prevalence, awareness and control of hypertension in Malaysia 1980 - 2017: A Systematic Review and Meta-Analysis. https://doi.org/10.1101/625004

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