What, if anything, is the true neurophysiological significance of rotational dynamics?

Abstract

Back in 2012, Churchland and his colleagues proposed that \"rotational dynamics\", uncovered through linear transformations of multidimensional neuronal data, represent a fundamental type of neuronal population processing in a variety of organisms, from the isolated leech central nervous system to the primate motor cortex. Here, we evaluated this claim using Churchlands own data and simple simulations of neuronal responses. We observed that rotational patterns occurred in neuronal populations when (1) there was a temporal shift in peak firing rates exhibited by individual neurons, and (2) the temporal sequence of peak rates remained consistent across different experimental conditions. Provided that such a temporal order of peak firing rates existed, rotational patterns could be easily obtained using a rather arbitrary computer simulation of neural activity; modeling of any realistic properties of motor cortical responses was not needed. Additionally, arbitrary traces, such as Lissajous curves, could be easily obtained from Churchlands data with multiple linear regression. While these observations suggest that temporal sequences of neuronal responses could be visualized as rotations with various methods, we express doubt about Churchland et al.s exaggerated assessment that such rotations are related to \"an unexpected yet surprisingly simple structure in the population response\", which \"explains many of the confusing features of individual neural responses.\" Instead, we argue that their approach provides little, if any, insight on the underlying neuronal mechanisms employed by neuronal ensembles to encode motor behaviors in any species.