Driving the scalability of DNA-based information storage systems

Tomek, K. J.; Volkel, K.; Simpson, A.; Hass, A. G.; Indermaur, E. W.; Tuck, J.; Keung, A. J.

doi:10.1101/591594

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bioRxiv · 10.1101/591594

Driving the scalability of DNA-based information storage systems

Tomek, K. J.·Volkel, K.·Simpson, A.·Hass, A. G.·Indermaur, E. W.·Tuck, J.·Keung, A. J.

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Abstract

The extreme density of DNA presents a compelling advantage over current storage media; however, in order to reach practical capacities, new approaches for organizing and accessing information are needed. Here we use chemical handles to selectively extract unique files from a complex database of DNA mimicking 5 TB of data and design and implement a nested file address system that increases the theoretical maximum capacity of DNA storage systems by five orders of magnitude. These advancements enable the development and future scaling of DNA-based data storage systems with reasonable modern capacities and file access capabilities.

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Tomek, K. J., Volkel, K., Simpson, A., Hass, A. G., Indermaur, E. W., Tuck, J., Keung, A. J.. 2019-03-29. Driving the scalability of DNA-based information storage systems. https://doi.org/10.1101/591594

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