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bioRxiv · 10.1101/542647

Transcriptome Dedifferentiation Observed in Animal Primary Cultures is Essential to Plant Reprogramming

Ogata, N.
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Abstract

Tissue culture environment liberate cells from ordinary laws of multi-cellular organisms. This liberation enables cells several behaviors, such as growth, dedifferentiation, acquisition of pluripotency, immortalization and reprogramming. Each phenomenon is relating to each other and hardly to determine. Recently, dedifferentiation of animal cell was determined and quantified in increasing information entropy of transcriptome. The increasing information entropy of transcriptome induced by tissue culture may reappear in plant cells too. Here we corroborated it. Measuring information entropies of transcriptomes during reprogramming of plant cells suggested that reprogramming is a combined phenomenon of dedifferentiation and re-differentiation.

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Ogata, N.. 2019-02-06. Transcriptome Dedifferentiation Observed in Animal Primary Cultures is Essential to Plant Reprogramming. https://doi.org/10.1101/542647

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