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bioRxiv · 10.1101/535716

HABIT - a webserver for interactive T cell neoepitope discovery

Martins, J.·Magalhaes, C.·Vieira, V.·Rocha, M.·Osorio, N. S.
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Abstract

Neoepitopes generated by amino acid variants specifically found in pathogens or cancer cells are gaining momentum in immunotherapy development. HABIT (HLA Binding InTelligence) is a web platform designed to generate and analyse machine learning-based T cell epitope predictions for improved neoepitope discovery. Availability and ImplementationHABIT is available at http://habit.evobiomed.com. Peptide-HLA binding predictions by NetMHCpan 4.0 and NetMHCIIpan 3.1 were implemented in a web application for interactive data exploration using shiny package powered by RStudio. Contactnosorio@med.uminho.pt Supplementary informationSupplementary data and video tutorials are available online.

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Martins, J., Magalhaes, C., Vieira, V., Rocha, M., Osorio, N. S.. 2019-02-04. HABIT - a webserver for interactive T cell neoepitope discovery. https://doi.org/10.1101/535716

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