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bioRxiv · 10.1101/429597

Chelation therapy using static magnetic field

Shaw, J.·Chakraborty, A.·Chatterjee, S.·Bhattacharyya, M.·Dasgupta, A. K.
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Abstract

Static magnetic field (SMF) is reported to mimic chelation agents. In thalassemia blood, SMF minimizes iron overloading effect. In such cells ROS level is reduced, in presence of moderate strength (70mT). Pilot study on transfusion dependent thalassemia, thalassemia carriers and normal red blood clearly indicate the differential effects of SMF on thalassemia, thalassemia carrier and normal cells. SMF also reduces ROS induced DNA damage in lymphocytes. A comparative study on the iron chelating drug deferasirox and SMF treated lymphocytes further confirm our main thesis. This non-invasive therapeutic regime for hemochromatosis may serve the dual purpose of treating, iron overloading and minimizing, cellular damage by lowering the ROS level.

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Shaw, J., Chakraborty, A., Chatterjee, S., Bhattacharyya, M., Dasgupta, A. K.. 2018-09-28. Chelation therapy using static magnetic field. https://doi.org/10.1101/429597

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