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bioRxiv · 10.1101/348227

VGLUT2 functions as a differential marker for hippocampal output neurons

Wozny, C.·Beed, P.·Nitzan, N.·Poessnecker, Y.·Rost, B. R.·Schmitz, D.
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Abstract

The subiculum is the gatekeeper between the hippocampus and cortical areas. Yet, the lack of a pyramidal cell-specific marker gene has made the analysis of the subicular area very difficult. Here we report that the vesicular-glutamate transporter 2 (VGLUT2) functions as a specific marker gene for subicular burst-firing neurons, and demonstrate that VGLUT2-Cre mice allow for Channelrhodopsin-2 (ChR2)-assisted connectivity analysis.

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Wozny, C., Beed, P., Nitzan, N., Poessnecker, Y., Rost, B. R., Schmitz, D.. 2018-06-17. VGLUT2 functions as a differential marker for hippocampal output neurons. https://doi.org/10.1101/348227

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