Higher order spherical harmonics reconstruction of fetal diffusion MRI with intensity correction

Deprez, M.; Price, A. N.; Christiaens, D.; Lockwood Estrin, G.; Cordero Grande, L.; Daducci, A.; Tournier, J.-D.; Rutherford, M. A.; Counsell, S.; Bach Cuadra, M.; Hajnal, J. V.

doi:10.1101/297341

bioRxiv · 10.1101/297341

Higher order spherical harmonics reconstruction of fetal diffusion MRI with intensity correction

Deprez, M.·Price, A. N.·Christiaens, D.·Lockwood Estrin, G.·Cordero Grande, L.·Daducci, A.·Tournier, J.-D.·Rutherford, M. A.·Counsell, S.·Bach Cuadra, M.·Hajnal, J. V.

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Abstract

We present a comprehensive method for reconstruction of fetal diffusion MRI signal using a higher order spherical harmonics representation, that includes motion, distortion and intensity correction. By applying constrained spherical deconvolution and whole brain tractography to reconstructed fetal diffusion MRI we are able to identify main WM tracts and anatomically plausible fiber crossings. The proposed methodology facilitates detailed investigation of developing brain connectivity and microstructure in-utero.

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Deprez, M., Price, A. N., Christiaens, D., Lockwood Estrin, G., Cordero Grande, L., Daducci, A., Tournier, J.-D., Rutherford, M. A., Counsell, S., Bach Cuadra, M., Hajnal, J. V.. 2018-04-08. Higher order spherical harmonics reconstruction of fetal diffusion MRI with intensity correction. https://doi.org/10.1101/297341

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