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bioRxiv · 10.1101/285197

Emergent orientation selectivity from random networks in mouse visual cortex

Pattadkal, J.·Mato, G.·van Vreeswijk, C.·Priebe, N. J.·hansel, d.
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Abstract

We study the connectivity principles underlying the emergence of orientation selectivity in primary visual cortex (V1) of mammals lacking an orientation map. We present a computational model in which random connectivity gives rise to orientation selectivity that matches experimental observations. It predicts that mouse V1 neurons should exhibit intricate receptive fields in the two-dimensional frequency domain, causing shift in orientation preferences with spatial frequency. We find evidence for these features in mouse V1 using calcium imaging and intracellular whole cell recordings.

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Pattadkal, J., Mato, G., van Vreeswijk, C., Priebe, N. J., hansel, d.. 2018-03-19. Emergent orientation selectivity from random networks in mouse visual cortex. https://doi.org/10.1101/285197

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