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bioRxiv · 10.1101/277509

VIGA: a sensitive, precise and automatic de novo VIral Genome Annotator.

Gonzalez-Tortuero, E.·Sutton, T. D.·Velayudhan, V.·Shkoporov, A. N.·Draper, L. A.·Stockdale, S. R.·Ross, R. P.·Hill, C.
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Abstract

Viral (meta)genomics is a rapidly growing field of study that is hampered by an inability to annotate the majority of viral sequences; therefore, the development of new bioinformatic approaches is very important. Here, we present a new automatic de novo genome annotation pipeline, called VIGA, to annotate prokaryotic and eukaryotic viral sequences from (meta)genomic studies. VIGA was benchmarked on a database of known viral genomes and a viral metagenomics case study. VIGA generated the most accurate outputs according to the number of coding sequences and their coordinates, outputs also had a lower number of non-informative annotations compared to other programs.

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Gonzalez-Tortuero, E., Sutton, T. D., Velayudhan, V., Shkoporov, A. N., Draper, L. A., Stockdale, S. R., Ross, R. P., Hill, C.. 2018-03-07. VIGA: a sensitive, precise and automatic de novo VIral Genome Annotator.. https://doi.org/10.1101/277509

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