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bioRxiv · 10.1101/276097

Spatial organization of the somatosensory cortex revealed by cyclic smFISH

Codeluppi, S.·Borm, L. E.·Zeisel, A.·La Manno, G.·van Lunteren, J. A.·Svensson, C. I.·Linnarsson, S.
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Abstract

The global efforts towards the creation of a molecular census of the brain using single-cell transcriptomics is generating a large catalog of molecularly defined cell types lacking spatial information. Thus, new methods are needed to map a large number of cell-specific markers simultaneously on large tissue areas. Here, we developed a cyclic single molecule fluorescence in situ hybridization methodology and defined the cellular organization of the somatosensory cortex using markers identified by single-cell transcriptomics.

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Codeluppi, S., Borm, L. E., Zeisel, A., La Manno, G., van Lunteren, J. A., Svensson, C. I., Linnarsson, S.. 2018-03-04. Spatial organization of the somatosensory cortex revealed by cyclic smFISH. https://doi.org/10.1101/276097

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