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bioRxiv · 10.1101/2025.10.21.679087

Human olfactory organoids as an in vitro model of the olfactory epithelium

Kim, K.-H.·Chauhan, A.·Kohanski, M. A.·Palmer, J. N.·Reed, D. R.·Cohen, N. A.·Jiang, P.·Wang, H.·Douglas, J. E.
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Abstract

Abstract/Key PointsO_LIA novel human olfactory epithelial organoid model has been generated from primary cell culture. C_LIO_LIHuman olfactory organoids exhibit immunostaining and gene expression for olfactory cells. C_LIO_LIOlfactory organoids mobilize Ca2+ in response to odorants, a surrogate for neuronal function. C_LI

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Kim, K.-H., Chauhan, A., Kohanski, M. A., Palmer, J. N., Reed, D. R., Cohen, N. A., Jiang, P., Wang, H., Douglas, J. E.. 2025-10-22. Human olfactory organoids as an in vitro model of the olfactory epithelium. https://doi.org/10.1101/2025.10.21.679087

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