Distinctive neurophysiological correlates of sound onset and offset perception in humans

Abstract

Accurate detection of sound onsets and offsets is vital for speech perception. Sound-onset event-related potentials (ERPs) have been well-characterised in electroencephalography (EEG) studies, but the characteristics of sound-offset ERPs have often been obscured by temporal confounds in experimental design. Here, two EEG studies were conducted in human listeners performing an interval duration discrimination task with (i) noise intervals in silence or (ii) silent intervals (gaps) in noise. Stimuli used in the active task were also presented under passive listening conditions. This design enabled us to investigate whether features of the offset ERP could be masked by task demands, and whether the usual temporal precedence of the onset cue in a sound influences the relative magnitude and shape of onset and offset ERPs. The morphology of the offset ERP was distinct from that of the onset ERP in both noise and silent interval duration discrimination tasks, even though the roles of onset and offset cues as initial versus final markers of interval duration were reversed. This observation corroborates evidence from animal studies that there are fundamental differences in brain mechanisms of onset and offset perception. In all experimental conditions, the amplitude of the offset ERP was one-third to one-half that of the onset ERP. Differences between active and passive listening conditions were largely explained by enhancement of ERPs for whichever cue (onset or offset) marked the end of the intervals compared in the duration discrimination task. However, this context dependence emerged in earlier ERP waves for offset than onset responses. Key points summaryO_LIOnset and offset event-related potentials (ERPs) differ in morphology and amplitude C_LIO_LIFor both onset and offset ERPs, P200 and later waves depend on behavioural context C_LIO_LIFor offset ERPs only, P100/N100 waves also depend on behavioural context C_LIO_LIEngagement in duration discrimination alters ERPs primarily for end-interval cues C_LI