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bioRxiv · 10.1101/2025.05.08.652817

Dynamics of oscillatory power subtends multiplexing of perceptual and mnemonic information within the premotor cortex

Marc, I. B.·Giuffrida, V.·Ramawat, S.·Bardella, G.·Ferraina, S.·Brunamonti, E.
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Abstract

Flexible behaviour requires decision-making that integrates both perceptual and mnemonic-related information. While the dorsal premotor cortex (PMd) is known to support decision-making based on perceptual computations, its contributions to decisions based on mnemonic information for motor planning are underexplored. Here, investigating local field potential (LFP) oscillations in PMd of monkeys performing a transitive inference task required the formation and retrieval of mnemonic representations of an arbitrarily defined rank order among perceptual items. Our results highlight that a dynamic interplay between lower frequencies (Theta, Alpha, Beta) and high-Gamma oscillatory activity of LFP reflects a mechanism for accessing and manipulating memory-related information underlying decision-making. These findings provide evidence that the PMd plays a role in multiplexing both perceptual and mnemonic information, extending its competence beyond the association of perceptual input with motor decisions.

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Marc, I. B., Giuffrida, V., Ramawat, S., Bardella, G., Ferraina, S., Brunamonti, E.. 2025-05-08. Dynamics of oscillatory power subtends multiplexing of perceptual and mnemonic information within the premotor cortex. https://doi.org/10.1101/2025.05.08.652817

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