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bioRxiv · 10.1101/2025.04.07.647662

ReCycled: A Tool to Reset the Start of Circular Bacterial Chromosomes

Somerville, V.·Schmid, M.·Dreier, M.·Engel, P.
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Abstract

Summary (two sentences)For many publicly available bacterial genomes the chromosome start is not set at the replication initiation protein. This is a burden for comparative genomics studies as the synteny between such genomes cannot readily be assessed. Here, we present ReCycled, a tool for identifying and resetting the start of circular bacterial chromosomes. Availability and implementationFreely available on GitHub at https://github.com/Freevini/ReCycled under the GPL-3.0 license. Runs on all tested GNU/Linux systems. ContactVincent Somerville, vincent@somerville.earth Supplementary InformationThe analyses, scripts and data to test the different pipelines are deposited online on zenodo (10.5281/zenodo.15170502).

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Somerville, V., Schmid, M., Dreier, M., Engel, P.. 2025-04-09. ReCycled: A Tool to Reset the Start of Circular Bacterial Chromosomes. https://doi.org/10.1101/2025.04.07.647662

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