Novel Biomolecular techniques in the analysis of Orthopaedic trabecular metal implants produced by additive manufacturing

Hurst, J.; Dunlop, D.; Oreffo, R.

doi:10.1101/2025.02.12.637860

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bioRxiv · 10.1101/2025.02.12.637860

Novel Biomolecular techniques in the analysis of Orthopaedic trabecular metal implants produced by additive manufacturing

Hurst, J.·Dunlop, D.·Oreffo, R.

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Abstract

Recent trends have seen an increase in the use of orthopaedic acetabular implants produced by additive manufacturing. These implants utilise novel trabecular metals with seemingly large variations in their structural designs. There is no available biomolecular comparisons between these different implants. We have therefore created novel techniques to image and analyse 5 different implants. Our results have shown differing responses of Human Bone Marrow Stem Cells cultured on these 5 different implants.

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Hurst, J., Dunlop, D., Oreffo, R.. 2025-02-17. Novel Biomolecular techniques in the analysis of Orthopaedic trabecular metal implants produced by additive manufacturing. https://doi.org/10.1101/2025.02.12.637860

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