Emergence of Candida auris in Minas Gerais, Brazil: Genomic Surveillance to inform Rapid Public Health Responses

Tome, L. M. R.; Camargo, D. R. A.; Bastos, R. W.; dos Santos, S. C. F.; Guimaraes, N. R.; Pedroso, S. H. S. P.; Silva, P. E. d. S. d.; Goes-Neto, A.; Figueredo, L. J. d. A.; Castro, G. d. C.; Rodrigues, A. M. R. N.; Cruzeiro, F. R. S.; Dutra, N. A. C.; Moura, J. B. P.; Pereira, G. d. C.; Faria, C. D.; Giovanetti, M.; Iani, F. C. d. M.; Alcantara, L. C. J.; Adelino, T. E. R.

doi:10.1101/2024.12.13.627932

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bioRxiv · 10.1101/2024.12.13.627932

Emergence of Candida auris in Minas Gerais, Brazil: Genomic Surveillance to inform Rapid Public Health Responses

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Abstract

Candida auris poses a significant global health threat due to its multidrug-resistance and outbreak potential. In this study, we report its emergence in Minas Gerais, Brazil, supported by genomic surveillance that identified Clade-IV isolates, suggested a potential introduction from Colombia, and detected a missense mutation associated with azole resistance.

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Tome, L. M. R., Camargo, D. R. A., Bastos, R. W., dos Santos, S. C. F., Guimaraes, N. R., Pedroso, S. H. S. P., Silva, P. E. d. S. d., Goes-Neto, A., Figueredo, L. J. d. A., Castro, G. d. C., Rodrigues, A. M. R. N., Cruzeiro, F. R. S., Dutra, N. A. C., Moura, J. B. P., Pereira, G. d. C., Faria, C. D., Giovanetti, M., Iani, F. C. d. M., Alcantara, L. C. J., Adelino, T. E. R.. 2024-12-16. Emergence of Candida auris in Minas Gerais, Brazil: Genomic Surveillance to inform Rapid Public Health Responses. https://doi.org/10.1101/2024.12.13.627932

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