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bioRxiv · 10.1101/2024.07.30.605815

CHANGES IN MUSCLE QUALITY FOLLOWING SHORT-TERM RESISTANCE TRAINING IN OLDER ADULTS: A COMPARISON OF ECHO INTENSITY AND TEXTURE ANALYSIS

Knowles, K. S.·Pagan, J. I.·Beausejour, J. P.·Mongold, S. J.·Anderson, A. W.·Stout, J. R.·Stock, M. S.
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Abstract

BackgroundSkeletal muscle echo intensity (EI) is associated with functional outcomes in older adults, but resistance training interventions have shown mixed results. Texture analysis has been proposed as a novel approach for assessing muscle quality, as it captures spatial relationships between pixels. PurposeTo examine changes in first-order (EI) and second-order (texture) features of muscle quality following lower-body resistance training in older adults. MethodsTwelve older adults (2 males, 10 females; mean {+/-} SD age = 70 {+/-} 5 years) completed 6 weeks of progressive resistance training, consisting of twice-weekly sessions at 85% of estimated 1RM. Pre- and post-intervention assessments included ultrasound imaging of the rectus femoris (RF) and vastus lateralis (VL), 5-repetition maximum (5RM) leg extension strength, and maximal voluntary isometric contraction (MVIC) force. Ultrasound images were analyzed for EI and texture features using gray-level co-occurrence matrix (GLCM) analysis. ResultsLarge improvements were observed in 5RM leg extension strength (p < 0.001, d = 2.09), MVIC force (p = 0.006, d = 0.969), and RF EI (uncorrected: p = 0.003, d = 0.727; corrected: p = 0.012, d = 0.864). No significant changes were observed in muscle size, VL EI, or texture features for either muscle. ConclusionsShort-term resistance training improved strength and RF muscle quality as measured by EI. However, texture analysis features were not sensitive to changes following training. These findings suggest that traditional EI measures may be more appropriate than texture analysis for tracking changes in muscle quality following resistance training in older adults. NEW & NOTEWORTHYWe studied muscle quality changes after 6 weeks of resistance training in older adults, comparing traditional EI to texture analysis. Despite significant strength gains, only RF EI improved, with minimal changes in muscle size, VL EI, or texture parameters. Surprisingly, texture analysis was less sensitive than traditional EI in detecting muscle quality changes. Our results suggest that conventional EI measures may be more suitable for evaluating short-term adaptations to resistance training in older adults.

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Knowles, K. S., Pagan, J. I., Beausejour, J. P., Mongold, S. J., Anderson, A. W., Stout, J. R., Stock, M. S.. 2024-07-31. CHANGES IN MUSCLE QUALITY FOLLOWING SHORT-TERM RESISTANCE TRAINING IN OLDER ADULTS: A COMPARISON OF ECHO INTENSITY AND TEXTURE ANALYSIS. https://doi.org/10.1101/2024.07.30.605815

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