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bioRxiv · 10.1101/2024.02.19.581046

Analysis of Poly(methyl methacrylate) Hydrogel IntradermalIrritation Test

Racheal, C.
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Abstract

This study employs the intradermal injection method to assess the skin irritation potential of domestically produced medical hydrogel. Healthy white rabbits received intradermal injections of 0.5% sodium chloride solution (control), 0.5% sodium chloride extract, and olive oil extract as test samples. Erythema and edema were observed at 24 and 72 hours post-injection, and the primary irritation index was determined. Results revealed a primary irritation index of 0 for domestically produced hydrogel, indicating no skin irritation response.

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Racheal, C.. 2024-02-23. Analysis of Poly(methyl methacrylate) Hydrogel IntradermalIrritation Test. https://doi.org/10.1101/2024.02.19.581046

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