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bioRxiv · 10.1101/2023.12.31.573798

A Comprehensive Allele Specific Expression Resource for the Equine Transcriptome

Heath, H. D.·Peng, S.·Szmatola, T.·Bellone, R. R.·Kalbfleish, T.·Petersen, J. L.·Finno, C. J.
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Abstract

BackgroundAllele-specific expression (ASE) analysis provides a nuanced view of cis-regulatory mechanisms affecting gene expression. ResultsIn this work, we introduce and highlight the significance of an equine ASE analysis, containing integrated long- and short-read RNA sequencing data, along with insight from histone modification data, from four healthy Thoroughbreds (2 mares and 2 stallions) across 9 tissues. ConclusionsThis valuable publicly accessible resource is poised to facilitate investigations into regulatory variation in equine tissues and foster a deeper understanding of the impact of allelic imbalance in equine health and disease at the molecular level.

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Heath, H. D., Peng, S., Szmatola, T., Bellone, R. R., Kalbfleish, T., Petersen, J. L., Finno, C. J.. 2024-01-02. A Comprehensive Allele Specific Expression Resource for the Equine Transcriptome. https://doi.org/10.1101/2023.12.31.573798

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