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bioRxiv · 10.1101/2023.09.22.559047

BAllC and BAllCools: Efficient Formatting and Operating for Single-Cell DNA Methylation Data

Tian, W.·Ding, W.·Ecker, J. R.
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Abstract

MotivationWith single-cell DNA methylation studies yielding vast datasets, existing data formats struggle with the unique challenges of storage and efficient operations, highlighting a need for improved solutions. ResultsBAllC (Binary All Cytosines) emerges as a tailored binary format for methylation data, addressing these challenges. BAllCools, its complementary software toolkit, enhances parsing, indexing, and querying capabilities, promising superior operational speeds and reduced storage needs. Availabilityhttps://github.com/jksr/ballcools Contactecker@salk.edu Supplementary informationSupplementary data are available at Bioinformatics online.

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Tian, W., Ding, W., Ecker, J. R.. 2023-09-25. BAllC and BAllCools: Efficient Formatting and Operating for Single-Cell DNA Methylation Data. https://doi.org/10.1101/2023.09.22.559047

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