MGX 2.0: Shotgun- and assembly-based metagenome and metatranscriptome analysis from a single source

Jaenicke, S.; Diedrich, S.; Goesmann, A.

doi:10.1101/2023.09.21.558800

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bioRxiv · 10.1101/2023.09.21.558800

MGX 2.0: Shotgun- and assembly-based metagenome and metatranscriptome analysis from a single source

Jaenicke, S.·Diedrich, S.·Goesmann, A.

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Abstract

Metagenomics studies have enabled scientists to analyze the genetic information of natural habitats or even complete ecosystems, including otherwise unculturable microbes. The processing of such datasets, however, remains a challenging task requiring extensive computational resources. MGX 2.0 is a versatile solution for the analysis and interpretation of microbial community sequence data. MGX 2.0 supports the processing of raw metagenomes and metatranscriptomes, but also enables assembly-based strategies, including downstream taxonomic binning, bin quality assessment, abundance quantification, and subsequent annotation coming from a single source. Due to the modular design of MGX, users are able to choose from a wide range of different methods for microbial community sequence data analysis, allowing them to directly compare between read-based and assembly-based approaches or to evaluate different strategies to analyze their data.

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Jaenicke, S., Diedrich, S., Goesmann, A.. 2023-09-23. MGX 2.0: Shotgun- and assembly-based metagenome and metatranscriptome analysis from a single source. https://doi.org/10.1101/2023.09.21.558800

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