Carbapenem- and cefiderocol-resistant Enterobacterales in surface waters in Kumasi, Ashanti Region, Ghana

Eger, E.; Homeier-Bachmann, T.; Adade, E.; Dreyer, S.; Heiden, S. E.; Tawiah, P. O.; Sylverken, A. A.; Knauf, S.; Schaufler, K.

doi:10.1101/2023.08.04.551947

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bioRxiv · 10.1101/2023.08.04.551947

Carbapenem- and cefiderocol-resistant Enterobacterales in surface waters in Kumasi, Ashanti Region, Ghana

Eger, E.·Homeier-Bachmann, T.·Adade, E.·Dreyer, S.·Heiden, S. E.·Tawiah, P. O.·Sylverken, A. A.·Knauf, S.·Schaufler, K.

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Abstract

This study investigated the presence of extended-spectrum {beta}-lactamase-producing Enterobacterales in selected surface waters in the Ashanti Region in Ghana. Subsequent genomic analysis revealed that one-fifth of the isolates were genotypically carbapenem-resistant. Phenotypic susceptibility testing not only confirmed their carbapenem resistance, but also uncovered two cefiderocol-resistant isolates.

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Eger, E., Homeier-Bachmann, T., Adade, E., Dreyer, S., Heiden, S. E., Tawiah, P. O., Sylverken, A. A., Knauf, S., Schaufler, K.. 2023-08-04. Carbapenem- and cefiderocol-resistant Enterobacterales in surface waters in Kumasi, Ashanti Region, Ghana. https://doi.org/10.1101/2023.08.04.551947

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