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bioRxiv · 10.1101/2023.08.03.551916

Positive feedback regulation of Pparγ1sv and Pparγ2 during adipogenesis in 3T3-L1 cells

Takenaka, Y.·Kakinuma, Y.·Inoue, I.
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Abstract

We have previously identified the novel splicing variant of mouse Ppar{gamma} (Ppar{gamma}1sv) and proposed the synergistic regulation of the early stage of adipocyte differentiation by Ppar{gamma}1sv and Ppar{gamma}2. Here, we report the finding of PPAR{gamma}-binding sites within the Ppar{gamma} gene locus and its importance in adipogenesis and propose the positive feedback regulation of Ppar{gamma}1sv and Ppar{gamma}2 expression during the adipocyte differentiation of 3T3-L1 cells.

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Takenaka, Y., Kakinuma, Y., Inoue, I.. 2023-08-04. Positive feedback regulation of Pparγ1sv and Pparγ2 during adipogenesis in 3T3-L1 cells. https://doi.org/10.1101/2023.08.03.551916

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