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bioRxiv · 10.1101/2023.06.27.546739

Identification of a recombinant human astrovirus type 5 strain from an acute gastroenteritis outbreak in Beijing, China

Mao, t.·Zhang, P.·Li, L.-l.·yang, m.·wang, y.·ma, y.·Li, D.-d.·li, j.·Duan, Z.-j.
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Abstract

Two samples positive for the same strain (2103CP) of human astrovirus (HAstV) were identified during an acute gastroenteritis outbreak in Beijing, China. A full genomic analysis showed that for both samples, open reading frame 1a (ORF1a) clustered with HAstV-1, whereas ORF1b and ORF2 clustered with HAstV-5. The recombination site was detected upstream of the region where ORF1a and ORF1b overlapped. Recombinant HAstV-5 strains were reported previously in China in 2013 and 2021. Our results indicate the need for continuous surveillance of the prevalence and evolution of this recombinant HAstV-5 in China.

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Mao, t., Zhang, P., Li, L.-l., yang, m., wang, y., ma, y., Li, D.-d., li, j., Duan, Z.-j.. 2023-06-28. Identification of a recombinant human astrovirus type 5 strain from an acute gastroenteritis outbreak in Beijing, China. https://doi.org/10.1101/2023.06.27.546739

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