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bioRxiv · 10.1101/2023.06.22.546173

High performers demonstrate greater neural synchrony than low performers across behavioral domains

Abstract

Heterogeneity in brain activity gives rise to heterogeneity in behavior, which in turn comprises our distinctive characteristics as individuals. Studying the path from brain to behavior, however, often requires making assumptions about how similarity in behavior scales with similarity in brain activity. Here, we expand upon recent work which proposes a theoretical framework for testing the validity of such assumptions. Using intersubject representational similarity analysis in two independent movie-watching fMRI datasets, we probe how brain-behavior relationships vary as a function of behavioral domain and participant sample. We find evidence that, in some cases, the neural similarity of two individuals is not correlated with behavioral similarity. Rather, individuals with higher behavioral scores are more similar to other high scorers whereas individuals with lower behavioral scores are dissimilar from everyone else. Ultimately, our findings motivate a more extensive investigation of both the structure of brain-behavior relationships and the tacit assumption that people who behave similarly will demonstrate shared patterns of brain activity.

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BibTeXRIS

Chamberlain, T. A., Corriveau, A., Song, H., Kwon, Y. H., Yoo, K., Chun, M., Rosenberg, M. D.. 2023-06-26. High performers demonstrate greater neural synchrony than low performers across behavioral domains. https://doi.org/10.1101/2023.06.22.546173

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