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bioRxiv · 10.1101/2023.04.11.536352

Trained recurrent neural networks develop phase-locked limit cycles in a working memory task

Abstract

Neural oscillations are ubiquitously observed in many brain areas. One proposed functional role of these oscillations is that they serve as an internal clock, or frame of reference. Information can be encoded by the timing of neural activity relative to the phase of such oscillations. In line with this hypothesis, there have been multiple empirical observations of such phase codes in the brain. Here we ask: What kind of neural dynamics support phase coding of information with neural oscillations? We tackled this question by analyzing recurrent neural networks (RNNs) that were trained on a working memory task. The networks were given access to an external reference oscillation and tasked to produce an oscillation, such that the phase difference between the reference and output oscillation maintains the identity of transient stimuli. We found that networks converged to stable oscillatory dynamics. Reverse engineering these networks revealed that each phase-coded memory corresponds to a separate limit cycle attractor. We characterized how the stability of the attractor dynamics depends on both reference oscillation amplitude and frequency, properties that can be experimentally observed. To understand the connectivity structures that underlie these dynamics, we showed that trained networks can be described as two phase-coupled oscillators. Using this insight, we condensed our trained networks to a reduced model consisting of two functional modules: One that generates an oscillation and one that implements a coupling function between the internal oscillation and external reference. In summary, by reverse engineering the dynamics and connectivity of trained RNNs, we propose a mechanism by which neural networks can harness reference oscillations for working memory. Specifically, we propose that a phase-coding network generates autonomous oscillations which it couples to an external reference oscillation in a multi-stable fashion. Author summaryMany of our actions are rhythmic--walking, breathing, digesting and more. It is not surprising that neural activity can have a strong oscillatory component. Indeed, such brain waves are common, and can even be measured using EEG from the scalp. Perhaps less obvious is the presence of such oscillations during non-rhythmic behavior--such as memory maintenance and other cognitive functions. Reports of these cognitive oscillations have accumulated over the years, and various theories were raised regarding their origin and utilization. In particular, oscillations have been proposed to serve as a clock signal that can be used for temporal-, or phase-coding of information in working memory. Here, we studied the dynamical systems underlying this kind of coding, by using trained artificial neural networks as hypothesis generators. We trained recurrent neural networks to perform a working memory task, while giving them access to a reference oscillation. We were then able to reverse engineer the learned dynamics of the networks. Our analysis revealed that phase-coded memories correspond to stable attractors in the dynamical landscape of the model. These attractors arose from the coupling of the external reference oscillation with oscillations generated internally by the network.

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BibTeXRIS

Pals, M., Macke, J. H., Barak, O.. 2023-04-11. Trained recurrent neural networks develop phase-locked limit cycles in a working memory task. https://doi.org/10.1101/2023.04.11.536352

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