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bioRxiv · 10.1101/2023.01.12.523736

BnIR: a multi-omics collaborative resource and tool platform for Brassica napus biological study

Qing-Yong, Y.·Yang, Z.·Wang, S.·Wei, L.·Huang, Y.·Liu, D.·Jia, Y.·Luo, C.·Lin, Y.·Liang, C.·Hu, Y.·Dai, C.·Guo, L.
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Abstract

In the post-GWAS era, multi-omics techniques have shown great power and potential for candidate gene mining and functional genomics research. However, due to the lack of effective data integration and multi-omics analysis platforms, such techniques have not still been applied widely in rapeseed, an important oil crop worldwide. Here, we constructed a rapeseed multi-omics database (BnIR; http://yanglab.hzau.edu.cn/BnIR), which provides datasets of six omics including genomics, transcriptomics, variomics, epigenetics, phenomics and metabolomics, as well as numerous "variation-gene expression-phenotype" associations by using multiple statistical methods. In addition, a series of multi-omics search and analysis tools are integrated to facilitate the browsing and application of these datasets. BnIR is the most comprehensive multi-omics database for rapeseed so far, and two case studies demonstrated its power to mine candidate genes associated with specific traits and analyze their potential regulatory mechanisms. Short SummaryIn this study, we developed BnIR (http://yanglab.hzau.edu.cn/BnIR), a multi-omics database for rapeseed that integrates six omics datasets and "variation-gene expression-phenotype" associations. The database is equipped with a range of multi-omics tools for streamlined browsing and analysis. Through multiple case studies, we demonstrated BnIRs potential to identify candidate genes associated with specific traits and investigate their regulatory mechanisms.

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Qing-Yong, Y., Yang, Z., Wang, S., Wei, L., Huang, Y., Liu, D., Jia, Y., Luo, C., Lin, Y., Liang, C., Hu, Y., Dai, C., Guo, L.. 2023-01-16. BnIR: a multi-omics collaborative resource and tool platform for Brassica napus biological study. https://doi.org/10.1101/2023.01.12.523736

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