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bioRxiv · 10.1101/2022.12.10.519861

Phantasus: web-application for visual and interactive gene expression analysis

Kleverov, M.·Zenkova, D.·Kamenev, V.·Sablina, M.·Artyomov, M.·Sergushichev, A.
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Abstract

Transcriptomic profiling became a standard approach to quantify a cell state, which led to accumulation of huge amount of public gene expression datasets. However, both reuse of these datasets or analysis of newly generated ones requires a significant technical expertise. Here we present Phantasus - a user-friendly web-application for interactive gene expression analysis which provide a streamlined access to more than 84000 public gene expression datasets, as well as allows analysis of user-uploaded datasets. Phantasus integrates an intuitive and highly interactive JavaScript-based heatmap interface with an ability to run sophisticated R-based analysis methods. Overall Phantasus allows to go all the way from loading, normalizing and filtering data to doing differential gene expression and downstream analysis. Phantasus can be accessed on-line at https://ctlab.itmo.ru/phantasus or https://artyomovlab.wustl.edu/phantasus or can be installed locally from Bioconductor (https://bioconductor.org/packages/phantasus). Phantasus source code is available at https://github.com/ctlab/phantasus under MIT licence.

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Kleverov, M., Zenkova, D., Kamenev, V., Sablina, M., Artyomov, M., Sergushichev, A.. 2022-12-12. Phantasus: web-application for visual and interactive gene expression analysis. https://doi.org/10.1101/2022.12.10.519861

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