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bioRxiv · 10.1101/2022.11.29.518395

HTRX: an R package for learning non-contiguous haplotypes associated with a phenotype

Yang, Y.·Lawson, D. J.
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Abstract

SummaryHaplotype Trend Regression with eXtra flexibility (HTRX) is an R package which uses cross-validation to learn sets of interacting features for a prediction. HTRX identifies haplotypes composed of non-contiguous single nucleotide polymorphisms (SNPs) associated with a phenotype. To reduce the space and computational complexity when investigating many features, we constrain the search by growing good feature sets using Cumulative HTRX, and limit the maximum complexity of a feature set. AvailabilityHTRX is implemented in R and is available under GPL-3 license from CRAN and Github at: https://github.com/YaolingYang/HTRX. Contactyaoling.yang@bristol.ac.uk

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Yang, Y., Lawson, D. J.. 2022-12-02. HTRX: an R package for learning non-contiguous haplotypes associated with a phenotype. https://doi.org/10.1101/2022.11.29.518395

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