bioRxiv · 10.1101/2022.07.30.502162
Known phyla dominate the RNA virome in Tara Oceans data, not new phyla as claimed
Abstract
The Tara Oceans project claimed to identify five new RNA virus phyla, two of which "are dominant in the oceans". However, their own assignments classify 28,353 of their putative RdRp-containing contigs to known phyla but only 886 (2.8%) to the five claimed new phyla combined. I mapped their reads to their contigs, finding that known phyla also account for a large majority (93.8%) of reads. I show that 510 of their putative viral contigs contain cellular proteins and further that predicted polymerase structures for their claimed phyla have incomplete and malformed palm domains, contradicting viral polymerase function and calling into question whether their putative polymerase sequences are derived from viruses.
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Edgar, R. C.. 2022-08-01. Known phyla dominate the RNA virome in Tara Oceans data, not new phyla as claimed. https://doi.org/10.1101/2022.07.30.502162
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