Language exposure and brain myelination in early development

Fibla, L.; Forbes, S. H.; McCarthy, J.; Mee, K.; Magnotta, V. A.; Deoni, S.; Cameron, D.; Spencer, J. P.

doi:10.1101/2022.05.31.493945

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bioRxiv · 10.1101/2022.05.31.493945

Language exposure and brain myelination in early development

Fibla, L.·Forbes, S. H.·McCarthy, J.·Mee, K.·Magnotta, V. A.·Deoni, S.·Cameron, D.·Spencer, J. P.

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Abstract

The language environment to which children are exposed has an impact on later language and cognitive abilities as well as on brain development; however, it is unclear how early such impacts emerge. This study investigates the effects of childrens early language environment and socioeconomic status (SES) on brain structure in infancy at both 6 and 30 months of age. We used magnetic resonance imaging (MRI) to quantify concentrations of myelin in specific fiber tracts in the brain. Our central question was whether Language ENvironment Analysis (LENA) measures from in-home recording devices and SES measures of maternal education and family income predicted myelin concentrations over development. Results show relationships between amount of in-home adult input and myelination in the white matter tracts most associated with language. Right hemisphere regions also show an association with SES, with older children from a higher SES background who were exposed to more adult input showing greater concentrations of myelin in language-related areas. We discuss these results in relation with the current literature and implications for future language research and intervention. Significance StatementThis is the first study to look at how brain myelination is impacted by language input and socioeconomic status early in development. We find robust relationships of both factors in language-related brain areas at 30 months of age.

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Fibla, L., Forbes, S. H., McCarthy, J., Mee, K., Magnotta, V. A., Deoni, S., Cameron, D., Spencer, J. P.. 2022-06-02. Language exposure and brain myelination in early development. https://doi.org/10.1101/2022.05.31.493945

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