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bioRxiv · 10.1101/2022.05.06.490965

A Standardized Ontology for Naming tRNA-derived RNAs Based on Molecular Origin

Holmes, A. D.·Chan, P. P.·Chen, Q.·Ivanov, P.·Drouard, L.·Polacek, N.·Kay, M. A.·Lowe, T. M.
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Abstract

Small RNAs processed from transfer RNA are recognized to have regulatory functions distinct from protein synthesis. This rapidly advancing field has led to a constellation of transcript nomenclatures. Building upon the accepted tRNA naming system and linking tRNA-derived small RNAs to their molecular sources, we propose an improved nomenclature. Facilitated by the tDRnamer system, it will promote inter-study comparisons leveraging a biologically-rooted nomenclature for this emerging class of intriguing regulators.

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Holmes, A. D., Chan, P. P., Chen, Q., Ivanov, P., Drouard, L., Polacek, N., Kay, M. A., Lowe, T. M.. 2022-05-08. A Standardized Ontology for Naming tRNA-derived RNAs Based on Molecular Origin. https://doi.org/10.1101/2022.05.06.490965

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