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bioRxiv · 10.1101/2022.04.11.487656

Super-Resolution NMR Spectroscopy using the Intersection of Non-Redundant Information on Resonance Groups

Lorieau, J. L.·Malooley, A.·Banerjee, I.
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Abstract

The resolution of spectra is a major limitation in the application of Nuclear Magnetic Resonance (NMR) spectroscopy to large and complex molecular systems. In this report, we introduce a technique to enhance the resolution of NMR spectra beyond the intrinsic limitations of a spectrometer for a single spectrum by using the Intersection of Non-Redundant Information on Resonance Groups (INIR). With INIR, we reconstruct 900-MHz (21.1T) spectra from a 500-MHz (11.7T) NMR spectrometer, which compare favorably to experimental 900-MHz spectra. INIR holds promise in significantly enhancing the resolution of NMR spectra and in extending the size and complexity of molecules studied by NMR.

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Lorieau, J. L., Malooley, A., Banerjee, I.. 2022-04-12. Super-Resolution NMR Spectroscopy using the Intersection of Non-Redundant Information on Resonance Groups. https://doi.org/10.1101/2022.04.11.487656

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