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bioRxiv · 10.1101/2021.12.21.473702

Tutorial: Investigating SARS-CoV-2 evolution and phylogeny using MNHN-Tree-Tools

Haschka, T.
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Abstract

The Covid-19 pandemic has caused at more than 3 million deaths by Mai this year [1]. It had a significant impact on the daily life and the global economy [2]. The virus has since its first recorded outbreak in China [3] mutated into new strains [4]. The Nextstrain [5] project has so far been monitoring the evolution of the virus. At the same time we were developing in our lab the MNHN-Tree-Tools [6] toolkit, primarily for the investigation of DNA repeat sequences. We have further extended MNHN-Tree-Tools [6] to guide phylogenetics. As such the toolkit has evolved into a high performance code, allowing for a fast investigation of millions of sequences. Given the context of the pandemic it became evident that we will use our versatile tool to investigate the evolution of SARS-CoV-2 sequences. Our efforts have cumulated in this tutorial that we share with the scientific community.

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Haschka, T.. 2021-12-23. Tutorial: Investigating SARS-CoV-2 evolution and phylogeny using MNHN-Tree-Tools. https://doi.org/10.1101/2021.12.21.473702

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