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bioRxiv · 10.1101/2021.11.17.469047

Awake ripples enhance emotional memory encoding in the human brain

Zhang, H.·Skelin, I.·Ma, S.·Paff, M.·Yassa, M. A.·Knight, R. T.·Lin, J. J.
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Abstract

Intracranial recordings from the human amygdala and the hippocampus during an emotional memory encoding and discrimination task reveal increased awake sharp-wave/ripples (aSWR) after encoding of emotional compared to neutral stimuli. Further, post-encoding aSWR-locked memory reinstatement in the amygdala and the hippocampus was predictive of later memory discrimination. These findings provide electrophysiological evidence that post-encoding aSWRs enhance memory for emotional events.

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Zhang, H., Skelin, I., Ma, S., Paff, M., Yassa, M. A., Knight, R. T., Lin, J. J.. 2021-11-19. Awake ripples enhance emotional memory encoding in the human brain. https://doi.org/10.1101/2021.11.17.469047

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