Palaeogenomics reveal a hybrid origin of the world's largest Camelus species

Yuan, J.; Westbury, M. V.; Chen, S.; Hu, J.; Zhang, F.; Wang, S.; Zhang, Z.; Wang, L.; Xiao, B.; Hou, X.; Li, F.; Lai, X.; Liu, W.; Sheng, G.

doi:10.1101/2021.10.14.464381

bioRxiv · 10.1101/2021.10.14.464381

Palaeogenomics reveal a hybrid origin of the world's largest Camelus species

Yuan, J.·Westbury, M. V.·Chen, S.·Hu, J.·Zhang, F.·Wang, S.·Zhang, Z.·Wang, L.·Xiao, B.·Hou, X.·Li, F.·Lai, X.·Liu, W.·Sheng, G.

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Abstract

The extinct Camelus knoblochi is known as the largest camel in genus Camelus, but its relationship to modern Camelus species remains unclear. In this study, we reported the first mitochondrial and nuclear analyses of seven Late Pleistocene C. knoblochi samples from Northeastern China. We found that they are inseparable to wild Bactrian camel on the matrilineal side, but belong to a distinct cluster on the biparental nuclear side. Further admixture proportion analyses suggested hybrid ancestry between both the ancestors of the modern wild and domesticated Bactrian camels, with ~65% contribution from the former and ~35% from the later. By calculating the coalescence time for three Camelus species above, we estimated the hybridization event occurred between approximately 0.8 and 0.33 Ma. We also used Bayesian skyline to reconstruct the maternal demographic trajectories for different Camelus to better compare their evolutionary histories. Our results provide molecular insights into C. knoblochi and fill in a vital piece in understanding the genus Camelus.

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Yuan, J., Westbury, M. V., Chen, S., Hu, J., Zhang, F., Wang, S., Zhang, Z., Wang, L., Xiao, B., Hou, X., Li, F., Lai, X., Liu, W., Sheng, G.. 2021-10-15. Palaeogenomics reveal a hybrid origin of the world's largest Camelus species. https://doi.org/10.1101/2021.10.14.464381

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